Human interferon lambda-1 (IFN-λ1/IL-29) modulates the Th1/Th2 response
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چکیده
منابع مشابه
Preparation and Characterization of PLGA Nanoparticles Containing Plasmid DNA Encoding Human IFN-lambda-1/IL-29
During the 15 years since the discovery of type III human interferons [IFN-λ1(IL-29), IFN-λ2(IL-28A), and IFN-λ3(IL-28B)], numerous biological properties such as anticancer, antiviral, and immunomodulatory activities of this new IFN family have been investigated. Several studies have shown that the encapsulation of pcDNA with PLGA nanoparticles (NPs) protects them against DNase enzyme action an...
متن کاملPreparation and Characterization of PLGA Nanoparticles Containing Plasmid DNA Encoding Human IFN-lambda-1/IL-29
During the 15 years since the discovery of type III human interferons [IFN-λ1(IL-29), IFN-λ2(IL-28A), and IFN-λ3(IL-28B)], numerous biological properties such as anticancer, antiviral, and immunomodulatory activities of this new IFN family have been investigated. Several studies have shown that the encapsulation of pcDNA with PLGA nanoparticles (NPs) protects them against DNase enzyme action an...
متن کاملHeterologous Expression of Human IL-29 (IFN-λ1) in Iranian Lizard Leishmania
Background: Interferons with diffrent functions such as antiviral, antiproliferative and immunomodulatory actions are effctive <span style="font-varia...
متن کاملheterologous expression of human il-29 (ifn-î»1) in iranian lizard leishmania
background: interferons with diffrent functions such as antiviral, antiproliferative and immunomodulatory actions are effctivemedications for a number of diseases. one of these new interferons (ifns) is interleukin-29 (il-29) belongs to the family of ifn-λ hasantiviral activity and its potent in accompanying with ifn-α in treatment of hcv infection has been evaluated (clinical trial phase ii).r...
متن کاملLambda interferon (IFN-lambda), a type III IFN, is induced by viruses and IFNs and displays potent antiviral activity against select virus infections in vivo.
Type III interferons (IFNs) (interleukin-28/29 or lambda interferon [IFN-lambda]) are cytokines with IFN-like activities. Here we show that several classes of viruses induce expression of IFN-lambda1 and -lambda2/3 in similar patterns. The IFN-lambdas were-unlike alpha/beta interferon (IFN-alpha/beta)-induced directly by stimulation with IFN-alpha or -lambda, thus identifying type III IFNs as I...
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ژورنال
عنوان ژورنال: Genes & Immunity
سال: 2007
ISSN: 1466-4879,1476-5470
DOI: 10.1038/sj.gene.6364382